What is VIP?
VIP (vasoactive intestinal peptide) is a naturally occurring neuropeptide with broad signaling roles. It is studied in specialized research contexts including immune regulation and biotoxin-related research models.
How VIP works (research mechanism)
VIP research focuses on VPAC-receptor signaling, with interest in immune modulation, inflammation, and vascular endpoints.
Primary research applications
Immune-regulation research
Studied for immune-signaling endpoints in models.
Inflammation research
Examined for anti-inflammatory signaling.
Biotoxin-illness research
Used in specialized research designs.
Research dosing reference
Research references commonly cite 50 mcg four times daily (intranasal model) over extended study windows. Reference values only - a specialized compound.
Reconstitution & handling
VIP ships as a lyophilized (freeze-dried) powder and must be reconstituted before use in any liquid research model. Allow the vial to reach room temperature, swab the stopper, then add bacteriostatic water slowly down the inside wall of the vial - never spray it directly onto the powder. Swirl gently until dissolved; do not shake, as shaking foams the solution and stresses the peptide. The volume of water you add sets the concentration: a 5 mg vial reconstituted with 2 mL yields 2,500 mcg/mL, so 0.1 mL measures 250 mcg. A correctly reconstituted VIP solution is clear; discard if it is cloudy or shows particulate.
Storage & stability
Store un-reconstituted VIP vials refrigerated and protected from light for long-term stability; the lyophilized form is robust and tolerates shipping. After reconstitution, refrigerate at 2-8C, keep away from light, and use within the typical research window of roughly two to four weeks. The benzyl alcohol in bacteriostatic water helps inhibit microbial growth across that period. Always label reconstituted vials with the concentration and date.
Common research pairings
Generally studied as a standalone specialized peptide.
How VIP compares
VIP occupies a specialized research niche distinct from the structural, metabolic, and cognitive peptides.
Safety & research considerations
Supplied for research use only; a specialized and expensive compound. Not for human consumption.
Sourcing, purity & Certificate of Analysis
Every lot of VIP sold by Peptides Factory Direct is third-party tested to a 99%+ purity target, with identity confirmed by mass spectrometry and purity quantified by HPLC. A Certificate of Analysis (COA) documenting these results is available on request and ties each vial to a tracked lot. Material ships nationwide to all 50 US states with cold-chain handling where appropriate and fast domestic dispatch. This documentation is what separates research-grade VIP from unverified material - quality is established before the vial ever reaches your lab.
How to order VIP for research
VIP can be ordered through the Peptides Factory Direct research portal as a one-time purchase or on a recurring research schedule (every 2 weeks, monthly, every 2 months, or every 3 months). Checkout requires confirming you are 21 or older, purchasing for laboratory research only, and that the product is not for human or animal consumption. Bulk and standing-order pricing is available - note it in your order. Open the order portal to view current research sizes and pricing.
Frequently asked questions
What is VIP researched for?
Immune regulation, inflammation, and biotoxin-related research, typically in an intranasal model. Research use only.
What sizes are stocked?
5 mg and 10 mg vials, with COA on request.
Related Specialty peptides
All Specialty peptides · Research guides & articles
External references: Peptides (Wikipedia) · U.S. Food and Drug Administration