What is CJC-1295?
CJC-1295 is a synthetic analog of growth-hormone-releasing hormone (GHRH). It is studied in two forms: "no DAC" (also called Mod GRF 1-29), which is short-acting, and "with DAC" (Drug Affinity Complex), which binds albumin for a markedly longer half-life in research models.
How CJC-1295 works (research mechanism)
CJC-1295 research focuses on stimulation of the pituitary to release growth hormone in pulses. The DAC version extends the active window, while the no-DAC version produces a sharper, shorter pulse often studied alongside a GHRP such as Ipamorelin for synergistic release.
Primary research applications
Growth-hormone release research
The central research theme is endogenous GH-pulse stimulation and the comparison of DAC vs no-DAC kinetics.
Body-composition models
It is studied for downstream effects on muscle and fat metabolism in research models.
GHRH + GHRP synergy studies
CJC-1295 + Ipamorelin is one of the most-studied research pairings for amplified GH pulses.
Research dosing reference
Research references commonly cite 200-300 mcg of the no-DAC form before rest periods on a 5-7 day schedule, or 1-2 mg of the DAC form one to two times weekly. Reference values only.
Reconstitution & handling
CJC-1295 ships as a lyophilized (freeze-dried) powder and must be reconstituted before use in any liquid research model. Allow the vial to reach room temperature, swab the stopper, then add bacteriostatic water slowly down the inside wall of the vial - never spray it directly onto the powder. Swirl gently until dissolved; do not shake, as shaking foams the solution and stresses the peptide. The volume of water you add sets the concentration: a 5 mg vial reconstituted with 2 mL yields 2,500 mcg/mL, so 0.1 mL measures 250 mcg. A correctly reconstituted CJC-1295 solution is clear; discard if it is cloudy or shows particulate.
Storage & stability
Store un-reconstituted CJC-1295 vials refrigerated and protected from light for long-term stability; the lyophilized form is robust and tolerates shipping. After reconstitution, refrigerate at 2-8C, keep away from light, and use within the typical research window of roughly two to four weeks. The benzyl alcohol in bacteriostatic water helps inhibit microbial growth across that period. Always label reconstituted vials with the concentration and date.
Common research pairings
CJC-1295 (no DAC) + Ipamorelin is the canonical research pairing; the GHRH analog and the GHRP are reported to act through complementary receptors.
How CJC-1295 compares
The DAC form trades fewer administrations for a longer, flatter profile; the no-DAC form is studied for sharper, more physiologic pulses. Choice depends on the research kinetics of interest.
Safety & research considerations
CJC-1295 is a research chemical without approved human use. For laboratory research only.
Sourcing, purity & Certificate of Analysis
Every lot of CJC-1295 sold by Peptides Factory Direct is third-party tested to a 99%+ purity target, with identity confirmed by mass spectrometry and purity quantified by HPLC. A Certificate of Analysis (COA) documenting these results is available on request and ties each vial to a tracked lot. Material ships nationwide to all 50 US states with cold-chain handling where appropriate and fast domestic dispatch. This documentation is what separates research-grade CJC-1295 from unverified material - quality is established before the vial ever reaches your lab.
How to order CJC-1295 for research
CJC-1295 can be ordered through the Peptides Factory Direct research portal as a one-time purchase or on a recurring research schedule (every 2 weeks, monthly, every 2 months, or every 3 months). Checkout requires confirming you are 21 or older, purchasing for laboratory research only, and that the product is not for human or animal consumption. Bulk and standing-order pricing is available - note it in your order. Open the order portal to view current research sizes and pricing.
Frequently asked questions
What is the difference between CJC-1295 with and without DAC?
DAC binds albumin for a long half-life (fewer administrations in research); no-DAC is short-acting and produces sharper GH pulses. Both are research-use-only.
What is CJC-1295 commonly paired with?
In research it is most often studied with Ipamorelin, a GHRP, for synergistic growth-hormone release.
What sizes are stocked?
2 mg and 5 mg vials, third-party tested, COA on request.
Is CJC-1295 FDA approved?
No, it is a research chemical and not for human or animal use.
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All Growth Hormone & Muscle peptides · Research guides & articles
External references: Peptides (Wikipedia) · U.S. Food and Drug Administration