AOD 9604 for Research

What is AOD 9604?

AOD 9604 is a modified fragment (residues 176-191) of human growth hormone, representing the region associated with fat metabolism. It is studied because it isolates the lipolytic portion of GH without the growth-signaling or glucose effects of the whole hormone.

How AOD 9604 works (research mechanism)

AOD 9604 research focuses on stimulation of lipolysis (fat breakdown) and inhibition of lipogenesis without acting on the IGF-1 axis or blood glucose - the defining research feature.

Primary research applications

Lipolysis research

Studied specifically for fat-metabolism endpoints in models.

Metabolic models without glucose effect

Useful where researchers want fat signaling isolated from blood-sugar variables.

Stubborn-fat research

Examined in models of resistant adipose tissue.

Research dosing reference

Research references commonly cite 300-600 mcg daily (often modeled in a fasted window) over 12-16 week study periods. Reference values only.

Reconstitution & handling

AOD 9604 ships as a lyophilized (freeze-dried) powder and must be reconstituted before use in any liquid research model. Allow the vial to reach room temperature, swab the stopper, then add bacteriostatic water slowly down the inside wall of the vial - never spray it directly onto the powder. Swirl gently until dissolved; do not shake, as shaking foams the solution and stresses the peptide. The volume of water you add sets the concentration: a 5 mg vial reconstituted with 2 mL yields 2,500 mcg/mL, so 0.1 mL measures 250 mcg. A correctly reconstituted AOD 9604 solution is clear; discard if it is cloudy or shows particulate.

Storage & stability

Store un-reconstituted AOD 9604 vials refrigerated and protected from light for long-term stability; the lyophilized form is robust and tolerates shipping. After reconstitution, refrigerate at 2-8C, keep away from light, and use within the typical research window of roughly two to four weeks. The benzyl alcohol in bacteriostatic water helps inhibit microbial growth across that period. Always label reconstituted vials with the concentration and date.

Common research pairings

Sometimes studied alongside GH-secretagogues in metabolic research designs.

How AOD 9604 compares

Unlike GLP-1 peptides that act on appetite, AOD 9604 isolates the fat-metabolism portion of GH and does not affect blood sugar - a distinct research mechanism.

Safety & research considerations

AOD 9604 is a research chemical not approved for human use. For laboratory research only.

Sourcing, purity & Certificate of Analysis

Every lot of AOD 9604 sold by Peptides Factory Direct is third-party tested to a 99%+ purity target, with identity confirmed by mass spectrometry and purity quantified by HPLC. A Certificate of Analysis (COA) documenting these results is available on request and ties each vial to a tracked lot. Material ships nationwide to all 50 US states with cold-chain handling where appropriate and fast domestic dispatch. This documentation is what separates research-grade AOD 9604 from unverified material - quality is established before the vial ever reaches your lab.

How to order AOD 9604 for research

AOD 9604 can be ordered through the Peptides Factory Direct research portal as a one-time purchase or on a recurring research schedule (every 2 weeks, monthly, every 2 months, or every 3 months). Checkout requires confirming you are 21 or older, purchasing for laboratory research only, and that the product is not for human or animal consumption. Bulk and standing-order pricing is available - note it in your order. Open the order portal to view current research sizes and pricing.

Frequently asked questions

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External references: Peptides (Wikipedia) · U.S. Food and Drug Administration