Everything below is third-person science education for qualified researchers. The compounds named are research-grade reference materials for laboratory and in-vitro use only - not for human or animal consumption, not drugs or supplements, and not approved by the FDA. Nothing here is medical advice, a diagnosis, or a recommendation to take, dose, or administer any substance, and no compound is claimed to change anyone's lab values. It describes which peptides scientists investigate in research models related to this marker.
What IGF-1 is
Insulin-like growth factor 1 (IGF-1) is a hormone produced largely in the liver in response to growth hormone (GH). In research it is used as a downstream readout of growth-hormone-axis activity because it is more stable in circulation than GH itself, which is released in short pulses. Scientists measure IGF-1 in cell and animal models to study growth, tissue turnover, and metabolic signaling.
Why IGF-1 shows up in peptide research
The growth-hormone axis is one of the most-studied pathways in peptide science, and IGF-1 is the marker researchers most often track when investigating it. The compounds studied here generally fall into two families: growth-hormone-releasing hormone (GHRH) analogs and growth-hormone-releasing peptides (GHRPs), which are investigated in models for how the body's own GH pulse and the resulting IGF-1 signaling behave.
Peptides studied in IGF-1-axis research
The following research peptides appear frequently in literature related to the GH/IGF-1 axis. They are reference materials for laboratory study, not treatments:
- CJC-1295 (no DAC) - a short-acting GHRH analog studied for pulsatile GH release
- Ipamorelin - a selective GHRP studied for clean GH-axis signaling
- Sermorelin - a GHRH(1-29) analog used as a reference GHRH-receptor agonist
- Tesamorelin - a stabilized GHRH analog studied in visceral-fat and GH-axis models
- IGF-1 LR3 - a long-acting IGF-1 analog studied at the receptor and myocyte level
Browse the full growth hormone and muscle research category for the complete set.
Important: research education only, not medical advice
This page does not diagnose, treat, cure, mitigate, or prevent any disease or condition, and it makes no claim that any compound alters a person's blood work. Laboratory markers are interpreted by licensed clinicians in a medical setting; that is outside the scope of this page.
The peptides referenced are sold by Peptides Factory Direct strictly for laboratory and in-vitro research use only. They are not for human or animal consumption. If you have questions about your own health or lab results, consult a licensed healthcare professional.
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Frequently asked questions
Does taking a peptide raise IGF-1?
This page makes no such claim. It is research education describing which peptides scientists study in models related to the GH/IGF-1 axis. The compounds are research-use-only reference materials, not treatments, and nothing here is advice to take any substance.
What peptides are studied around the IGF-1 axis?
Literature on the growth-hormone axis commonly involves GHRH analogs (CJC-1295 no-DAC, Sermorelin, Tesamorelin) and GHRPs (Ipamorelin), plus IGF-1 LR3 as a downstream analog. All are laboratory research materials only.
Is IGF-1 a peptide?
IGF-1 is a peptide hormone the body produces. As a research reference material, IGF-1 LR3 is a long-acting analog studied in vitro. None of these are for human or animal consumption.
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External references: U.S. Food and Drug Administration · Peptide (Wikipedia)