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Growth Hormone Axis - SubQ

CJC-1295 No DAC Research Reference

CJC-1295 No DAC is a GHRH analog that stimulates pituitary GHRH receptors to promote pulsatile endogenous GH release. No-DAC versions are short acting and often timed around fasted or bedtim...

Research reference only. This is an educational, mechanism-level reference for an investigational research compound - not medical advice, a prescription, or a protocol to follow. Reconstitution, dosing, and pharmacokinetic figures are research-reference values for laboratory context only. Products are research-use-only, not for human or animal consumption, and not FDA approved. Confirm all concentration math and review with a qualified clinician before any formal research use.
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Mechanism of action

CJC-1295 No DAC is a GHRH analog that stimulates pituitary GHRH receptors to promote pulsatile endogenous GH release. No-DAC versions are short acting and often timed around fasted or bedtime GH-axis windows.

Half-life & pharmacokinetics

Half-life: Short acting.

Human pharmacokinetics are not standardized. Treat exposure as short acting unless compound-specific data or formal formulation labeling indicates otherwise.

Research dosing reference

100-300 mcg one to three times daily.

Dose interpretation (U-100 units)

Target doseU-100 units
100 mcg4 units
200 mcg8 units
300 mcg12 units

Units are concentration-specific - confirm against your actual reconstitution volume.

Reconstitution & concentration

VialPreferred reconstitutionFinal concentration
5 mg2 mL BAC Water0.025 mg/unit

Injection timing

Often used before bed or during fasted windows to align with GH-axis signaling and reduce food-related interference.

Beginner escalation

Begin conservatively while monitoring hunger, edema, sleep quality, glucose response, and tingling/carpal-tunnel-like symptoms.

Side-effect mitigation

Monitor water retention, increased hunger, flushing, glucose variability, joint stiffness, or tingling. Periodic IGF-1 and glucose monitoring may be appropriate in longer protocols.

Stack compatibility

GH-axis agents stack most logically with complementary GH secretagogues; avoid overbuilding GH-axis stacks without monitoring IGF-1, glucose, and edema response.

Storage & stability

Lyophilized: refrigerated or controlled cool storage. Reconstituted: refrigerated, protected from heat/light, and handled aseptically.

Protocol duration & reassessment

GH-axis protocols should reassess every 8-12 weeks: IGF-1, fasting glucose/A1c where appropriate, edema, sleep quality, hunger, body-composition objectives, and continued need.

Frequently asked questions

What is CJC-1295 No DAC and how does it work?

CJC-1295 No DAC is a GHRH analog that stimulates pituitary GHRH receptors to promote pulsatile endogenous GH release. No-DAC versions are short acting and often timed around fasted or bedtime GH-axis windows.

What is the half-life of CJC-1295 No DAC?

CJC-1295 No DAC: Short acting. Human pharmacokinetics are not standardized. Treat exposure as short acting unless compound-specific data or formal formulation labeling indicates otherwise.

How is CJC-1295 No DAC reconstituted for research?

Preferred reconstitution for the 5 mg vial is 2 mL BAC Water, giving 0.025 mg/unit. Always confirm concentration math before any use. Research use only.

Is CJC-1295 No DAC FDA approved?

No. CJC-1295 No DAC is an investigational research-use-only compound - not for human or animal consumption and not FDA approved.

All research reference · Research guides

External references: Peptide (Wikipedia) · U.S. Food and Drug Administration

CJC-1295 No DAC is an investigational research-use-only compound, not for human or animal consumption, not FDA approved, and not intended to diagnose, treat, cure, or prevent disease. This reference is not medical advice.