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What is Selank?
Selank is a synthetic heptapeptide derived from the immunomodulatory peptide tuftsin, developed in Russia. It is studied for anxiolytic (anti-anxiety) and cognitive endpoints without the sedation associated with classic anxiolytics.
How Selank works (research mechanism)
Selank research focuses on modulation of GABAergic and monoamine signaling and on brain-derived neurotrophic factor (BDNF) expression, with interest in anxiety and focus endpoints.
Primary research applications
Anxiolytic research
Studied for anxiety endpoints without sedation in models.
Cognitive / focus research
Examined for attention and mental-clarity variables.
Neuroprotection and immune research
Its tuftsin lineage links it to immune-signaling studies.
Research dosing reference
Research references commonly cite 250-500 mcg daily across 2-4 week cycles. Reference values only.
Reconstitution & handling
Selank ships as a lyophilized (freeze-dried) powder and must be reconstituted before use in any liquid research model. Allow the vial to reach room temperature, swab the stopper, then add bacteriostatic water slowly down the inside wall of the vial - never spray it directly onto the powder. Swirl gently until dissolved; do not shake, as shaking foams the solution and stresses the peptide. The volume of water you add sets the concentration: a 5 mg vial reconstituted with 2 mL yields 2,500 mcg/mL, so 0.1 mL measures 250 mcg. A correctly reconstituted Selank solution is clear; discard if it is cloudy or shows particulate.
Storage & stability
Store un-reconstituted Selank vials refrigerated and protected from light for long-term stability; the lyophilized form is robust and tolerates shipping. After reconstitution, refrigerate at 2-8C, keep away from light, and use within the typical research window of roughly two to four weeks. The benzyl alcohol in bacteriostatic water helps inhibit microbial growth across that period. Always label reconstituted vials with the concentration and date.
Common research pairings
Selank + Semax is a common cognitive-research pairing (anxiety plus focus endpoints).
How Selank compares
Selank is studied for anxiety endpoints where Semax is studied more for focus and BDNF; the two are complementary in cognitive research.
Safety & research considerations
Selank is a research chemical not approved for human use. For laboratory research only.
Selank research reference data
The figures below are reference values compiled from the research literature for laboratory study design only. They are not instructions for any living subject. See the full Selank research reference for complete detail and citations.
Half-life and exposure. Short acting
Pharmacokinetics (research reference). Human pharmacokinetics are not standardized. Treat exposure as short acting unless compound-specific data or formal formulation labeling indicates otherwise.
Selank dose-reference table
| Reference dose | Units (U-100 syringe) |
|---|---|
| 300 mcg | 6 units |
| 600 mcg | 12 units |
| 1000 mcg | 20 units |
Reconstitution and concentration by vial size
| Vial | Reconstitute with | Concentration |
|---|---|---|
| 10 mg | 2 mL BAC Water | 0.050 mg/unit |
| 30 mg | 3 mL BAC Water preferred for cleaner concentration | 0.100 mg/unit |
Research timing. Daytime or situational use is common unless sleep-specific. Avoid first-time use before critical tasks until response is understood.
Dose-escalation reference. Titrate based on sedation, stimulation, headache, focus, sleep quality, or emotional response. More is not always better with neuroactive peptides.
Monitoring in research models. Monitor headache, fatigue, paradoxical stimulation, sedation, sleep disruption, or emotional flattening. Avoid overlapping multiple neuroactive agents initially.
Reassessment cadence. Use short, interpretable blocks or situational protocols. Reassess after 2-4 weeks for sleep, mood, focus, headaches, stimulation/sedation, and whether continued use is justified.
Stacking notes (research). May pair with complementary neuropeptides, mitochondrial agents, or sleep protocols, but single-variable testing is preferred for interpretability.
Sourcing, purity & Certificate of Analysis
Every lot of Selank sold by Peptides Factory Direct is third-party tested to a 99%+ purity target, with identity confirmed by mass spectrometry and purity quantified by HPLC. A Certificate of Analysis (COA) documenting these results is available on request and ties each vial to a tracked lot. Material ships nationwide to all 50 US states with cold-chain handling where appropriate and fast domestic dispatch. This documentation is what separates research-grade Selank from unverified material - quality is established before the vial ever reaches your lab.
How to order Selank for research
Selank can be ordered through the Peptides Factory Direct research portal as a one-time purchase or on a recurring research schedule (every 2 weeks, monthly, every 2 months, or every 3 months). Checkout requires confirming you are 21 or older, purchasing for laboratory research only, and that the product is not for human or animal consumption. Bulk and standing-order pricing is available - note it in your order. Open the order portal to view current research sizes and pricing.
Frequently asked questions
What is Selank researched for?
Anxiolytic and cognitive endpoints without sedation, plus neuroprotection models. Research use only.
What is Selank paired with?
Most often Semax in cognitive-research designs.
What sizes are stocked?
5 mg and 10 mg vials, third-party tested, COA on request.
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External references: Peptides (Wikipedia) · U.S. Food and Drug Administration